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It is thought to be the first such resignation of its kind and was extensively covered in today's newspapers.
Some questioned her motives, others backed her principled stand - while the Mail plumped for this:
After a cursory assessment of the UK’s policy in the Middle East, her resignation letter widened into a critique of the recent Cabinet reshuffle, implying that she had deeper domestic political grievances that found an outlet in her unhappiness with the misery inflicted upon the people of Gaza
More: The overriding question from Baroness Warsi's resignation