"Her faux sophistication on these particular issues has been ridiculous," he says at a private event. "Everybody can see the moves that she's making, the things that she's saying and I find them disreputable."
The pair have also unfollowed one another on social media.
In recent weeks amid the war in Gaza, Owens has said there has been "collapsing support" for Israel.
On her Daily Wire show she also said "If I'm walking through Jerusalem and they say 'these are the Muslim quarters, this is where the Muslims are allowed to live', that doesn't feel like [...] freedom to me."
Although not publicly responding to Shapiro comments, some have pointed out that shortly after the clip of Shapiro speaking gained traction, Owens tweeted: "Blessed are the peacemakers: for they shall be called the children of God." At the end she wrote, "You cannot serve both God and money."
Blessed are the peacemakers: for they shall be called the children of God. Blessed are they which are persecuted for righteousness' sake: for theirs is the kingdom of heaven. Blessed are ye, when men shall revile you, and persecute you, and shall say all manner of evil against\u2026
Hours after a video was posted in which Ben Shapiro said that Candace Owens' rhetoric on Israel has been "absolutely disgraceful," Owens posted these tweets, which were her first in two days.\n\nAdding a note here to say that while the tweets themselves in this context is not\u2026
She has also been liking tweets suggesting that she will create her own show on Twitter/X, as former Fox News host Tucker Carlson has done. She announced yesterday that she will be sitting down to talk to Carlson.
Tomorrow I will be sitting down to chat exclusively with Tucker Carlson. \n\nWhat an honor. \n\n\ud83d\udd25\ud83d\udd25\ud83d\udd25
Shapiro is Jewish and has publicly shared his support for Israel, and the two have come to heads before about the issue. Shapiro had previously criticised her for defending Kanye West, as well as publicly scolding Owens for retweeting Max Blumenthal who he said "spends his life covering for Jew-haters and stumping for Israel's destruction".